The 100,000m2 mixed-use development includes residential (57,000m2), offices (17,500m2), retail, hotel , education, healthcare and leisure space, plus parking.
A statement from the London Borough of Lewisham said: "The council can confirm that the planning permission and section 106 agreement for the Lewisham Gateway scheme have been completed. The Compulsory Purchase Order relating to properties on the Gateway site was confirmed in April."
Lewisham Gateway is a joint venture between Taylor Wimpey and Muse Developments, a subsidiary of Morgan Sindall.
